Species-specific interactions of Src family tyrosine kinases regulate Chlamydia intracellular growth and trafficking

mBio. 2011 May 17;2(3):e00082-11. doi: 10.1128/mBio.00082-11. Print 2011.

Abstract

Src family kinases (SFKs) regulate key cellular processes and are emerging as important targets for intracellular pathogens. In this commentary, we briefly review the role of SFKs in bacterial pathogenesis and highlight new work on the role of SFKs during the intracellular cycle of Chlamydia species.

Publication types

  • Comment

MeSH terms

  • Chlamydia / enzymology*
  • Chlamydia / pathogenicity*
  • Humans
  • Virulence Factors / genetics*
  • Virulence Factors / metabolism*
  • src-Family Kinases / genetics*
  • src-Family Kinases / metabolism*

Substances

  • Virulence Factors
  • src-Family Kinases