Targeted synthesis of a 2D ordered porous organic framework for drug release

Chem Commun (Camb). 2011 Jun 14;47(22):6389-91. doi: 10.1039/c1cc00084e. Epub 2011 May 6.

Abstract

A novel 2D porous organic framework based on the nucleophilic substitution of cyanuric chloride has been designed and synthesized successfully, which possesses an ordered structure, permanent porosity and drug release ability towards ibuprofen.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Drug Carriers / chemical synthesis
  • Drug Carriers / chemistry*
  • Ibuprofen / chemistry*
  • Porosity
  • Triazines / chemical synthesis*
  • Triazines / chemistry

Substances

  • Drug Carriers
  • PAF-6 compound
  • Triazines
  • cyanuric chloride
  • Ibuprofen