MK-801 analogues: molecular properties required for recognition by the N-methyl-D-aspartate receptor

Prog Clin Biol Res. 1990:361:513-8.

Authors

P D Leeson¹, K James, R W Carling, E H Wong, R Baker

Affiliation

¹ Merck Sharp and Dohme Research Laboratories, Neuroscience Research Centre, Harlow, Essex, U.K.

PMID: 2149766

No abstract available

MeSH terms

Animals
Anticonvulsants / chemistry
Anticonvulsants / metabolism
Anticonvulsants / pharmacology*
Binding Sites
Brain / metabolism
Brain / ultrastructure
Dizocilpine Maleate / chemistry
Dizocilpine Maleate / metabolism
Dizocilpine Maleate / pharmacology*
Membranes / metabolism
Models, Molecular
Molecular Structure
Rats
Receptors, N-Methyl-D-Aspartate / antagonists & inhibitors
Receptors, N-Methyl-D-Aspartate / metabolism
Structure-Activity Relationship

Substances

Anticonvulsants
Receptors, N-Methyl-D-Aspartate
Dizocilpine Maleate