Abstract
Paired nasopharyngeal and oropharyngeal swabs collected from 533 children hospitalized with lower respiratory tract infection were assessed by multiplex reverse transcription-PCR. Oropharyngeal swabs increased the number of viral infections detected by 15%, compared to collection of a nasopharyngeal swab alone. This advantage was most pronounced for detection of influenza, parainfluenza, and adenovirus.
Publication types
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Evaluation Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Child
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Child, Preschool
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Female
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Humans
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Infant
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Infant, Newborn
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Male
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Nasopharynx / virology
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Oropharynx / virology*
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Respiratory Tract Infections / diagnosis*
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Respiratory Tract Infections / virology*
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Reverse Transcriptase Polymerase Chain Reaction / methods
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Sensitivity and Specificity
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Specimen Handling / methods*
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Virology / methods
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Virus Diseases / diagnosis*
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Virus Diseases / virology*
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Viruses / isolation & purification*