[Autism and ADHD across the life span. Differential diagnoses or comorbidity?]

Nervenarzt. 2011 May;82(5):573-80. doi: 10.1007/s00115-010-3239-6.
[Article in German]

Abstract

Exclusion criteria of the DSM-IV-TR and ICD-10 do prevent dual diagnoses of attention deficit hyperactivity disorder (ADHD) and autism spectrum disorders (ASD). However, inattention, impulsivity and hyperactivity are amongst the most frequent associated symptoms of ASD. Psychopathological, neuropsychological, brain imaging and genetic studies suggest possible pathophysiological links between ASD and ADHD. Thus, standard diagnostic procedures for both disorders should assess the presence of potential comorbid symptoms of the other disorder. Treatment strategies for ADHD symptoms in the context of ASD overlap with those for patients with ADHD, but lower dosages and slower titration might be recommendable.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Adrenergic Uptake Inhibitors / adverse effects
  • Adrenergic Uptake Inhibitors / therapeutic use
  • Antipsychotic Agents / adverse effects
  • Antipsychotic Agents / therapeutic use
  • Atomoxetine Hydrochloride
  • Attention Deficit Disorder with Hyperactivity / diagnosis*
  • Attention Deficit Disorder with Hyperactivity / drug therapy
  • Attention Deficit Disorder with Hyperactivity / epidemiology*
  • Attention Deficit Disorder with Hyperactivity / physiopathology
  • Brain / drug effects
  • Brain / physiopathology
  • Central Nervous System Stimulants / adverse effects
  • Central Nervous System Stimulants / therapeutic use
  • Child
  • Child Development Disorders, Pervasive / diagnosis*
  • Child Development Disorders, Pervasive / drug therapy
  • Child Development Disorders, Pervasive / epidemiology*
  • Child Development Disorders, Pervasive / physiopathology
  • Comorbidity
  • Diagnosis, Differential
  • Humans
  • Propylamines / adverse effects
  • Propylamines / therapeutic use
  • Risperidone / adverse effects
  • Risperidone / therapeutic use

Substances

  • Adrenergic Uptake Inhibitors
  • Antipsychotic Agents
  • Central Nervous System Stimulants
  • Propylamines
  • Atomoxetine Hydrochloride
  • Risperidone