[The research practice of anti-arrhythmic agents targeting on potassium ion channel]

Yao Xue Xue Bao. 2011 Jan;46(1):12-8.
[Article in Chinese]

Abstract

Due to the complicated pathogenesis of cardiac arrhythmia, the safe and effective therapeutic strategies for cardiac arrhythmia remain an urgent medical problems in the recent years. In this paper, we introduced the research practice of anti-arrhythmic agents targeting on potassium ion channel. The research progress of anti-arrhythmic agents in up-to-date literatures were also reviewed and prospected.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Amiodarone / analogs & derivatives
  • Amiodarone / chemistry
  • Amiodarone / pharmacology
  • Amiodarone / therapeutic use
  • Animals
  • Anti-Arrhythmia Agents / chemistry
  • Anti-Arrhythmia Agents / pharmacology*
  • Anti-Arrhythmia Agents / therapeutic use
  • Arrhythmias, Cardiac / drug therapy*
  • Arrhythmias, Cardiac / physiopathology
  • Dronedarone
  • Humans
  • Hydantoins
  • Imidazolidines / chemistry
  • Imidazolidines / pharmacology
  • Imidazolidines / therapeutic use
  • Molecular Structure
  • Piperazines / chemistry
  • Piperazines / pharmacology
  • Piperazines / therapeutic use
  • Potassium Channel Blockers / pharmacology*
  • Potassium Channel Blockers / therapeutic use
  • Potassium Channels / drug effects*

Substances

  • Anti-Arrhythmia Agents
  • Hydantoins
  • Imidazolidines
  • Piperazines
  • Potassium Channel Blockers
  • Potassium Channels
  • azimilide
  • Dronedarone
  • Amiodarone