Genomic characterization of two avian paramyxovirus type 2 isolates from chickens in China

Virus Genes. 2011 Aug;43(1):55-9. doi: 10.1007/s11262-011-0604-x. Epub 2011 Apr 2.

Abstract

The complete genome sequences were determined for avian paramyxovirus type 2 (APMV-2) strains F8 and NK isolated from chickens in China. Both strains had a genome of 14,904 nucleotides (nt) in length, which followed the "rule of six". Each genome consisted of six genes in the order 3'-N-P-M-F-HN-L-5', with a 55-nt leader at the 3' end and a 154-nt trailer at the 5' end. Sequence alignment and phylogenetic analysis showed that APMV-2 strains F8 and NK shared the highest sequence identity with APMV-2 prototype strain Yucaipa, being classified in the same subgroup as strains Yucaipa, England and Kenya, while strain Bangor represented another subgroup of APMV-2. Among the APMVs, APMV-2 strains F8 and NK exhibited a closer evolutionary relationship with APMV-7 and APMV-8 representative strains.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 3' Untranslated Regions
  • 5' Untranslated Regions
  • Animals
  • Avulavirus / genetics*
  • Avulavirus / isolation & purification*
  • Avulavirus Infections / veterinary*
  • Avulavirus Infections / virology
  • Chickens
  • China
  • Cluster Analysis
  • Gene Order
  • Genes, Viral
  • Genome, Viral*
  • Molecular Sequence Data
  • Phylogeny
  • Poultry Diseases / virology*
  • RNA, Viral / genetics*
  • Sequence Alignment
  • Sequence Analysis, DNA*

Substances

  • 3' Untranslated Regions
  • 5' Untranslated Regions
  • RNA, Viral

Associated data

  • GENBANK/HQ896023
  • GENBANK/HQ896024