Full-length genome sequence of a simian immunodeficiency virus from a wild-captured sun-tailed monkey in Gabon provides evidence for a species-specific monophyletic SIVsun lineage

AIDS Res Hum Retroviruses. 2011 Nov;27(11):1237-41. doi: 10.1089/AID.2011.0076. Epub 2011 May 20.

Abstract

Since the first characterization of SIVsun (L14 strain) from a sun-tailed monkey (Cercopithecus solatus) in Gabon in 1999, no further information exists about the evolutionary history and geographic distribution of this lentivirus. Here, we report the full-length molecular characterization of a second SIVsun virus (SIVsunK08) naturally infecting a wild-caught sun-tailed monkey. The SIVsunK08 strain was most closely related to SIVsunL14 and clustered with members of the SIVmnd-1/SIVlhoest group. SIVsunK08 shared identical functional motifs in the LTR, Gag and Env proteins with SIVsunL14. Our data indicate that C. solatus is naturally infected with a monophyletic SIVsun strain.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Animals, Wild / virology*
  • Cercopithecus / classification
  • Cercopithecus / virology*
  • Evolution, Molecular
  • Gabon
  • Genome, Viral / genetics*
  • Human Immunodeficiency Virus Proteins / genetics
  • Molecular Sequence Data
  • Monkey Diseases / virology
  • Phylogeny
  • Sequence Analysis, DNA*
  • Simian Acquired Immunodeficiency Syndrome / virology*
  • Simian Immunodeficiency Virus / classification
  • Simian Immunodeficiency Virus / genetics*
  • Species Specificity

Substances

  • Human Immunodeficiency Virus Proteins

Associated data

  • GENBANK/FR751162