Folic acid-functionalized two-photon absorbing nanoparticles for targeted MCF-7 cancer cell imaging

Chem Commun (Camb). 2011 Jul 14;47(26):7323-5. doi: 10.1039/c1cc10739a. Epub 2011 Mar 18.

Abstract

We report a facile strategy to synthesize folic acid-functionalized two-photon absorbing (TPA) nanoparticles with aggregation-induced emission for targeted cancer cell imaging using a two-photon fluorescence microscope.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Absorption
  • Breast Neoplasms / metabolism*
  • Breast Neoplasms / pathology*
  • Cell Line, Tumor
  • Female
  • Folic Acid / chemistry*
  • Folic Acid / metabolism*
  • Humans
  • Hydrophobic and Hydrophilic Interactions
  • Molecular Imaging / methods*
  • Nanoparticles / chemistry*
  • Phosphatidylethanolamines / chemistry
  • Photons*
  • Polyethylene Glycols / chemistry
  • Surface Properties

Substances

  • 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-methoxy-poly(ethylene glycol 2000)
  • Phosphatidylethanolamines
  • Polyethylene Glycols
  • Folic Acid