Discovering herbal functional groups of traditional Chinese medicine

Stat Med. 2012 Mar 30;31(7):636-42. doi: 10.1002/sim.4146. Epub 2011 Mar 17.

Abstract

For the traditional Chinese medicine (TCM), a prescription for a patient often contains several herbs. Some herbs are often used together in prescriptions, and these herbs can be considered as a functional group. In this paper, we propose an approach for discovering herbal functional groups from a large set of prescriptions recorded in TCM books. These functional groups are allowed to overlap with each other. Our approach is validated with a simulation study and applied to a data set containing thousands of TCM prescriptions.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Computer Simulation
  • Drug Discovery / methods*
  • Drug Discovery / statistics & numerical data*
  • Drug Prescriptions
  • Drugs, Chinese Herbal / chemistry*
  • Drugs, Chinese Herbal / therapeutic use
  • Humans
  • Medicine, Chinese Traditional*

Substances

  • Drugs, Chinese Herbal