Hepatocellular adenomas: current update on genetics, taxonomy, and management

J Comput Assist Tomogr. 2011 Mar-Apr;35(2):159-66. doi: 10.1097/RCT.0b013e31820bad61.

Abstract

Hepatocellular adenomas (HCAs) are uncommon, benign hepatocellular neoplasms that commonly occur in young women. Recent advances in pathology and cytogenetics have thrown fresh light on the pathogenesis of HCAs leading to classification of HCAs into 3 distinct subtypes, each with a characteristic epidemiology, histopathology, oncogenesis, and imaging findings. The aim of the article was to provide a comprehensive review of contemporary taxonomy of HCAs, with an emphasis on cross-sectional imaging findings and management.

Publication types

  • Review

MeSH terms

  • Adenoma, Liver Cell / diagnosis*
  • Adenoma, Liver Cell / genetics*
  • Adenoma, Liver Cell / therapy
  • Genetic Predisposition to Disease / genetics*
  • Humans
  • Liver Neoplasms / diagnosis*
  • Liver Neoplasms / genetics*
  • Liver Neoplasms / therapy
  • Magnetic Resonance Imaging / methods
  • Prognosis
  • Tomography, X-Ray Computed / methods