Association between metabolic syndrome and estimated glomerular filtration rate in older Koreans based on data from the third Korean National Health and Nutrition Examination Survey

Australas J Ageing. 2011 Mar;30(1):16-21. doi: 10.1111/j.1741-6612.2010.00440.x.

Abstract

Aim: To examine the association between metabolic syndrome (MetS) and renal function in older Koreans.

Methods: A total of 1270 people aged 60 years and older who participated in the third Korean National Health and Nutrition Examination Survey were included in this study.

Results: After adjusting for confounding factors, central obesity, high-density lipoprotein cholesterol and fasting glucose were significantly associated with decreased renal function in men. In women, however, each component of MetS with the exception of fasting glucose was not associated with renal function. The odds ratios for MetS were 2.548 in men and 1.454 in women after adjustment for confounding variables; both were statistically significant. The odds ratio of decreased renal function increased as the number of components of MetS increased.

Conclusion: The results of this study suggest that MetS may be an independent risk factor for decreased renal function in older population as well.

MeSH terms

  • Age Factors
  • Aged
  • Aged, 80 and over
  • Aging / ethnology*
  • Asian People / statistics & numerical data*
  • Blood Glucose / analysis
  • Chi-Square Distribution
  • Cholesterol, HDL / blood
  • Cross-Sectional Studies
  • Female
  • Glomerular Filtration Rate*
  • Health Surveys
  • Humans
  • Kidney / physiopathology*
  • Kidney Diseases / blood
  • Kidney Diseases / ethnology*
  • Kidney Diseases / physiopathology
  • Male
  • Metabolic Syndrome / blood
  • Metabolic Syndrome / ethnology*
  • Metabolic Syndrome / physiopathology
  • Middle Aged
  • Nutrition Surveys
  • Obesity / ethnology
  • Odds Ratio
  • Regression Analysis
  • Republic of Korea / epidemiology
  • Risk Assessment
  • Risk Factors
  • Sex Factors

Substances

  • Blood Glucose
  • Cholesterol, HDL