Abstract
HIV-infected persons are at heightened risk for recurrent community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) infections, but there are limited data regarding the molecular characterization of these events. We describe an HIV-infected patient with 24 soft tissue infections and multiple colonization events. Molecular genotyping from 33 nonduplicate isolates showed all strains were USA300, Panton-Valentine leukocidin (PVL) and arginine catabolic mobile element (ACME) positive, and genetically related.
Publication types
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Case Reports
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Adult
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Bacterial Toxins / genetics
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Bacterial Typing Techniques
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Cluster Analysis
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Community-Acquired Infections / diagnosis*
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Community-Acquired Infections / microbiology
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Electrophoresis, Gel, Pulsed-Field
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Exotoxins / genetics
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Genotype
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HIV Infections / complications*
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Humans
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Interspersed Repetitive Sequences
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Leukocidins / genetics
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Male
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Methicillin-Resistant Staphylococcus aureus / isolation & purification*
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Molecular Typing
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Recurrence
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Staphylococcal Infections / diagnosis*
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Staphylococcal Infections / microbiology
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Virulence Factors / genetics
Substances
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Bacterial Toxins
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Exotoxins
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Leukocidins
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Panton-Valentine leukocidin
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Virulence Factors