Aprepitant (Emend) significantly increases sirolimus levels in patients undergoing allogeneic hematopoietic SCT

MeSH terms

• Adult
• Aged
• Antiemetics / pharmacology*
• Aprepitant
• Drug Interactions
• Female
• Hematopoietic Stem Cell Transplantation / methods*
• Humans
• Immunosuppressive Agents / administration & dosage
• Immunosuppressive Agents / blood
• Immunosuppressive Agents / pharmacokinetics*
• Male
• Middle Aged
• Morpholines / pharmacology*
• Retrospective Studies
• Sirolimus / administration & dosage
• Sirolimus / blood
• Sirolimus / pharmacokinetics*
• Tacrolimus / administration & dosage
• Tacrolimus / blood
• Transplantation, Homologous
• Young Adult