A laser system composed of two lasers phase-locked onto an Optical Frequency Comb Synthesizer (OFCS), operating around 1083 nm, was developed. An absolute frequency precision of 6x10(-13) at 1s, limited by the OFCS, was measured with a residual rms phase-noise of 71 mrad and 87 mrad for the two phase-locks, respectively. Multiplex spectroscopy on 1083 nm Helium transitions with this set-up is demonstrated. Generalization of this system to a larger number of OFCS assisted laser sources for wider frequency separations, even in other spectral regions, is discussed.