Oxidative biaryl coupling of thiophenes and thiazoles with arylboronic acids through palladium catalysis: otherwise difficult C4-selective C-H arylation enabled by boronic acids

Angew Chem Int Ed Engl. 2011 Mar 1;50(10):2387-91. doi: 10.1002/anie.201007060. Epub 2011 Jan 31.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alzheimer Disease / drug therapy
  • Amyloid Precursor Protein Secretases / antagonists & inhibitors
  • Amyloid Precursor Protein Secretases / metabolism
  • Boronic Acids / chemistry*
  • Boronic Acids / therapeutic use
  • Carbon / chemistry
  • Catalysis
  • Cyclic N-Oxides / chemistry
  • Humans
  • Hydrogen / chemistry
  • Oxidation-Reduction
  • Palladium / chemistry*
  • Protease Inhibitors / chemical synthesis
  • Protease Inhibitors / chemistry
  • Protease Inhibitors / therapeutic use
  • Stereoisomerism
  • Thiazoles / chemistry*
  • Thiophenes / chemistry*

Substances

  • Boronic Acids
  • Cyclic N-Oxides
  • Protease Inhibitors
  • Thiazoles
  • Thiophenes
  • Palladium
  • Carbon
  • Hydrogen
  • Amyloid Precursor Protein Secretases
  • TEMPO