High on-clopidogrel platelet reactivity: genotyping can help to optimize antiplatelet treatment

Thromb Res. 2011 Jul;128(1):92-5. doi: 10.1016/j.thromres.2011.01.012. Epub 2011 Feb 24.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Blood Platelets / drug effects*
  • Blood Platelets / physiology
  • Clopidogrel
  • Dose-Response Relationship, Drug
  • Female
  • Genotype
  • Humans
  • Male
  • Middle Aged
  • Platelet Aggregation / drug effects
  • Platelet Aggregation / genetics
  • Platelet Aggregation Inhibitors / administration & dosage
  • Platelet Aggregation Inhibitors / pharmacology
  • Platelet Function Tests
  • Polymorphism, Genetic
  • Receptors, Purinergic P2Y12 / genetics
  • Ticlopidine / administration & dosage
  • Ticlopidine / analogs & derivatives*
  • Ticlopidine / pharmacology

Substances

  • P2RY12 protein, human
  • Platelet Aggregation Inhibitors
  • Receptors, Purinergic P2Y12
  • Clopidogrel
  • Ticlopidine