A ruthenium antimetastasis agent forms specific histone protein adducts in the nucleosome core

Chemistry. 2011 Mar 21;17(13):3562-6. doi: 10.1002/chem.201100298. Epub 2011 Feb 23.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Crystallography, X-Ray
  • Cymenes
  • Histones / chemistry*
  • Histones / metabolism
  • Molecular Structure
  • Nucleosomes / chemistry*
  • Nucleosomes / metabolism
  • Organometallic Compounds / chemistry*
  • Ruthenium / chemistry*
  • Ruthenium / pharmacology*

Substances

  • Cymenes
  • Histones
  • Nucleosomes
  • Organometallic Compounds
  • dichloro(4-cymene)(1,3,5-triaza-7-phosphatricyclo(3.3.1.1)decane)ruthenium(II)
  • Ruthenium