Osteoarthritis year 2010 in review: genetics

Osteoarthritis Cartilage. 2011 Apr;19(4):342-5. doi: 10.1016/j.joca.2011.01.020. Epub 2011 Feb 12.

Abstract

At the 2010 Osteoarthritis Research Society International (OARSI) congress in Brussels I was asked to present on "Genetics" in the "Year in Review" session. This gave me an opportunity to reflect on the talk that I gave on the same topic at the 2007 OARSI congress in Ft Lauderdale, Florida. My 2007 talk was very upbeat and ended with the hostage to fortune statement "The next few years will provide tremendous clarity in our genetic understanding of osteoarthritis".

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Genetic Predisposition to Disease
  • Genomics
  • Growth Differentiation Factor 5 / genetics
  • Humans
  • Interleukin 1 Receptor Antagonist Protein / genetics
  • Iodide Peroxidase / genetics
  • Iodothyronine Deiodinase Type II
  • Mutation*
  • Osteoarthritis / genetics*

Substances

  • GDF5 protein, human
  • Growth Differentiation Factor 5
  • IL1RN protein, human
  • Interleukin 1 Receptor Antagonist Protein
  • Iodide Peroxidase