Usefulness of combined PET/CT for patient with epithelial ovarian cancer showing recurrence based on tumor marker CA125

Tokai J Exp Clin Med. 2007 Mar 20;32(1):23-7.

Abstract

We report the case of a 41-year-old patient with epithelial ovarian cancer of stage IIIc. One year and nine months after completion of chemotherapy performed after surgery, the level of the tumor marker CA125 began to increase gradually. Conventional computed tomography (CT) and magnetic resonance imaging (MRI) were performed, but the recurrence site could not be determined clearly. However, combined positron emission tomography/computed tomography (PET/CT) revealed a metastasis in the right external iliac lymph node. This allowed commencement of chemotherapy at an early recurrent stage and subsequently the level of CA125 showed a significant decrease.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Agents / therapeutic use
  • Biomarkers, Tumor / metabolism*
  • CA-125 Antigen / metabolism*
  • Carcinoma, Ovarian Epithelial
  • Female
  • Humans
  • Lymphatic Metastasis / diagnosis
  • Neoplasms, Glandular and Epithelial / metabolism
  • Neoplasms, Glandular and Epithelial / pathology
  • Neoplasms, Glandular and Epithelial / prevention & control
  • Neoplasms, Glandular and Epithelial / therapy
  • Ovarian Neoplasms / metabolism
  • Ovarian Neoplasms / pathology
  • Ovarian Neoplasms / prevention & control
  • Ovarian Neoplasms / therapy
  • Positron-Emission Tomography / methods*
  • Recurrence
  • Tomography, X-Ray Computed / methods*

Substances

  • Antineoplastic Agents
  • Biomarkers, Tumor
  • CA-125 Antigen