We have analyzed the efficacy of nootropic drug pantogam in the treatment of hyperkinetic disorders in children aged 6-12 years. The results of the randomized placebo-controlled trial demonstrated the decrease of major symptoms of hyperkinetic disorders (inattention, hyperactivity, impulsivity), comorbid mental and behavior disorders, the improvement of cognitive functions in the group of children treated with pantogam during 6 weeks and the absence of significant changes in the placebo group. It has been concluded that pantogam is effective in the treatment of hyperkinetic disorders in children.