Targeting STAT3 signaling in pancreatic cancer promotes antiapoptotic gene expression

Pancreas. 2011 Mar;40(2):323-4. doi: 10.1097/MPA.0b013e318204ea7b.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Apoptosis*
  • Cell Line, Tumor
  • Humans
  • Inhibitor of Apoptosis Proteins / genetics
  • Pancreatic Neoplasms / genetics
  • Pancreatic Neoplasms / metabolism*
  • Pancreatic Neoplasms / pathology
  • RNA Interference
  • RNA, Messenger / metabolism
  • Reverse Transcriptase Polymerase Chain Reaction
  • STAT3 Transcription Factor / genetics
  • STAT3 Transcription Factor / metabolism*
  • Signal Transduction* / genetics
  • Survivin
  • Time Factors
  • Transfection
  • bcl-X Protein / genetics

Substances

  • BCL2L1 protein, human
  • BIRC5 protein, human
  • Inhibitor of Apoptosis Proteins
  • RNA, Messenger
  • STAT3 Transcription Factor
  • STAT3 protein, human
  • Survivin
  • bcl-X Protein