Loss of the association between cuff number and peritonitis may be related to implementation of new strategies of prevention. Daily application of antibiotic prophylaxis at the peritoneal dialysis exit site is a very effective one. Update of peritoneal dialysis-related infections recommendations published by the international society of peritoneal dialysis presents some evolutions in diagnosis techniques and treatments. Renal transplant recipients under belatacept have significant better renal function and less cardio-vascular risk factors compared to patients under cyclosporine A. Six month administration of anti-CMV prophylaxis in seronegative recipients has shown less CMV disease at 12 month follow-up. The correction of anemia up to 13-15 g/dl was associated with a better quality of life and a better graft function at 2 years follow up.