Reversal of hypercoagulability with hydroxyethyl starch during transplantation: a case series

J Clin Anesth. 2011 Feb;23(1):61-5. doi: 10.1016/j.jclinane.2009.10.021.

Abstract

During transplant surgery, clot formation resulting in life-threatening thromboembolic phenomena or graft loss may be a consequence unless close monitoring of coagulation and anticoagulation treatment is instituted in a timely manner. Three cases with a hypercoagulable state, as determined by thrombelastography at the time of surgery, but whose hypercoagulation was gradually attenuated with hydroxyethyl starch infusion during transplantation, are presented.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Diabetes Mellitus, Type 1 / surgery
  • Humans
  • Hydroxyethyl Starch Derivatives / administration & dosage
  • Hydroxyethyl Starch Derivatives / therapeutic use*
  • Infusions, Intravenous
  • Intestines / transplantation
  • Intraoperative Complications / drug therapy*
  • Kidney Failure, Chronic / surgery
  • Kidney Transplantation / adverse effects
  • Male
  • Middle Aged
  • Monitoring, Intraoperative
  • Organ Transplantation / adverse effects*
  • Pancreas Transplantation / adverse effects
  • Plasma Substitutes / administration & dosage
  • Plasma Substitutes / therapeutic use*
  • Thrombelastography
  • Thrombophilia / drug therapy*

Substances

  • Hydroxyethyl Starch Derivatives
  • Plasma Substitutes