Activation of "inert" alkenyl/aryl C-O bond and its application in cross-coupling reactions

Bi-Jie Li; Da-Gang Yu; Chang-Liang Sun; Zhang-Jie Shi

doi:10.1002/chem.201002273

Activation of "inert" alkenyl/aryl C-O bond and its application in cross-coupling reactions

Chemistry. 2011 Feb 7;17(6):1728-59. doi: 10.1002/chem.201002273. Epub 2011 Jan 17.

Authors

Bi-Jie Li¹, Da-Gang Yu, Chang-Liang Sun, Zhang-Jie Shi

Affiliation

¹ Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Green Chemistry Center, Peking University, Beijing 100871, P.R. China.

PMID: 21274921
DOI: 10.1002/chem.201002273

Abstract

Enol and phenol functionalities are very common in organic molecules. Utilization of these materials is very appealing in organic synthesis because they are important alternatives to organohalides in cross-coupling reactions. In this review, we summarize the transition-metal-catalyzed cross-coupling of enol- and phenol-based electrophiles, including phosphates, sulfonates, ethers, carboxylates, and phenolates.