Melanoma of the middle ear: initial presentation, Fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography imaging and follow up

J Laryngol Otol. 2011 May;125(5):536-9. doi: 10.1017/S0022215110002872. Epub 2011 Jan 27.

Abstract

Background: We present a rare case of primary mucosal melanoma of the middle ear imaged with 18F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (FDG-PET/CT).

Method: Clinical, radiological, intra-operative and histological findings are discussed.

Results: An 88-year-old woman presented with intermittent otorrhoea of the left ear for several months. Otoscopy revealed a livid protrusion of the tympanic membrane. Melanoma was not suspected initially, but was established on transmembranous biopsy. Pre-operative 18F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography revealed a mass lesion in the left tympanic cavity with high fluoro-deoxyglucose uptake, as well as an ipsilateral intraparotid lymph node metastasis. The patient underwent surgical treatment. The diagnosis of melanoma was confirmed histologically.

Conclusion: In this rare case, clinical, radiological and surgical findings led to the diagnosis of a primary mucosal melanoma of the middle ear.

Publication types

  • Case Reports

MeSH terms

  • Aged, 80 and over
  • Biopsy
  • Diagnosis, Differential
  • Ear Neoplasms / diagnostic imaging*
  • Ear Neoplasms / pathology
  • Ear Neoplasms / surgery
  • Ear, Middle*
  • Fatal Outcome
  • Female
  • Fluorodeoxyglucose F18
  • Humans
  • Melanoma / diagnostic imaging*
  • Melanoma / pathology
  • Melanoma / surgery
  • Neck Dissection
  • Neoplasm Staging
  • Parotid Neoplasms / diagnosis*
  • Parotid Neoplasms / secondary
  • Parotid Neoplasms / surgery
  • Radionuclide Imaging
  • Radiopharmaceuticals
  • Rare Diseases / diagnostic imaging*

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18