Employment-based abstinence reinforcement as a maintenance intervention for the treatment of cocaine dependence: post-intervention outcomes

Addiction. 2011 May;106(5):960-7. doi: 10.1111/j.1360-0443.2011.03364.x. Epub 2011 Mar 7.

Abstract

Aims: Due to the chronicity of cocaine dependence, practical and effective maintenance interventions are needed to sustain long-term abstinence. We sought to assess the effects of long-term employment-based reinforcement of cocaine abstinence after discontinuation of the intervention.

Design: Participants who initiated sustained opiate and cocaine abstinence during a 6-month abstinence reinforcement and training program worked as data entry operators and were randomly assigned to a group that could work independently of drug use (control, n = 24), or an abstinence-contingent employment (n = 27) group that was required to provide cocaine- and opiate-negative urine samples to work and maintain maximum rate of pay.

Setting: A non-profit data entry business.

Participants: Unemployed welfare recipients who persistently used cocaine while in methadone treatment.

Measurements: Urine samples and self-reports were collected every 6 months for 30 months.

Findings: During the employment year, abstinence-contingent employment participants provided significantly more cocaine-negative samples than controls (82.7% and 54.2%; P = 0.01, OR = 4.61). During the follow-up year, the groups had similar rates of cocaine-negative samples (44.2% and 50.0%; P = 0.93) and human immunodeficiency virus risk behaviors. Participants' social, employment, economic and legal conditions were similar in the two groups across all phases of the study.

Conclusions: Employment-based reinforcement effectively maintains long-term cocaine abstinence, but many patients relapse to use when the abstinence contingency is discontinued, even after a year of abstinence-contingent employment. Relapse could be prevented in many patients by leaving employment-based abstinence reinforcement in place indefinitely, which could be facilitated by integrating it into typical workplaces.

Trial registration: ClinicalTrials.gov NCT00249496.

Publication types

  • Randomized Controlled Trial
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Baltimore
  • Behavior Therapy / methods*
  • Breath Tests
  • Cocaine-Related Disorders / rehabilitation*
  • Cocaine-Related Disorders / urine
  • Employment / organization & administration*
  • Female
  • Humans
  • Male
  • Methadone / therapeutic use
  • Narcotics / therapeutic use
  • Opiate Substitution Treatment
  • Outcome Assessment, Health Care / statistics & numerical data*
  • Patient Compliance*
  • Reinforcement, Psychology*
  • Risk-Taking
  • Salaries and Fringe Benefits
  • Secondary Prevention
  • Substance Abuse Detection

Substances

  • Narcotics
  • Methadone

Associated data

  • ClinicalTrials.gov/NCT00249496