[A case of sigmoid colon cancer with synchronous multiple liver and lung metastases, who survived 25-month after combination of chemotherapy and metastasectomy]

Abstract

A 60-year-old male underwent sigmoidectomy for sigmoid colon cancer with synchronous multiple liver and lung metastases. Six weeks after the sigmoidectomy, mFOLFOX6 + bevacizumab (Bmab) was initiated. After 7 courses, lung tumors were almost disappeared and liver tumors shrunken up to 69% in size, and metastasectomy of liver tumors was performed with R0 resection. Pathological examination disclosed that tumor response to chemotherapy was Grade 2. mFOLFOX6 + Bmab, FOLFIRI + Bmab, and cetuximab were administered after liver surgery before the patient died 25 months after the sigmoidectomy. Combination therapy of metastasectomy and intensive chemotherapy might benefit to prolong survival of the patient.