Comparison of 2% chlorhexidine and 5.25% sodium hypochlorite irrigating solutions on postoperative pain: a randomized clinical trial

Indian J Dent Res. 2010 Oct-Dec;21(4):523-7. doi: 10.4103/0970-9290.74225.

Abstract

Aim: To compare the levels of postoperative pain after cleaning and shaping of root canals using two different root canal irrigants for debridement.

Materials and methods: Forty patients with irreversible pulpitis, pulp necrosis and non-vital teeth exhibiting acute apical periodontitis requiring root canal treatment were included. At random, canals were cleaned and shaped with the following protocols. 2% chlorhexidine solution in group I and 5.25% sodium hypochlorite solution in group II were used as an irrigants. Access cavities were closed with a sterile cotton pellet and cavit. The patients recorded degree of pain at various time intervals after cleaning and shaping on a visual analogue scale for 1 week.

Results: The mean pain score for group I was between 0.65 and 3.35 and for group II was between 0.95 and 4.50. There was significant difference in the pain level between the two groups only at 6 th hour postoperatively (P<0.05) and the pain was more in sodium hypochlorite group.

Conclusions: More pain was present in teeth irrigated using 5.25% sodium hypochlorite when compared to that in teeth irrigated using 2% chlorhexidine solution. Significant difference in pain level was present only at 6th hour postoperatively, and at all other periods (24 th hour, 4 th and 7 th days) there was no significant difference in pain level between the two groups.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Anti-Infective Agents, Local / therapeutic use*
  • Calcium Sulfate / therapeutic use
  • Chlorhexidine / therapeutic use*
  • Dental Cements / therapeutic use
  • Dental Pulp Necrosis / therapy
  • Follow-Up Studies
  • Humans
  • Pain Measurement
  • Pain, Postoperative / prevention & control*
  • Periapical Periodontitis / therapy
  • Polyvinyls / therapeutic use
  • Pulpitis / therapy
  • Root Canal Filling Materials / therapeutic use
  • Root Canal Irrigants / therapeutic use*
  • Root Canal Preparation / methods*
  • Sodium Hypochlorite / therapeutic use*
  • Tooth, Nonvital / therapy
  • Young Adult
  • Zinc Oxide / therapeutic use

Substances

  • Anti-Infective Agents, Local
  • Dental Cements
  • Polyvinyls
  • Root Canal Filling Materials
  • Root Canal Irrigants
  • Cavit
  • Sodium Hypochlorite
  • Chlorhexidine
  • Zinc Oxide
  • Calcium Sulfate