Acyl transfer from phosphocholine lipids to melittin

Chem Commun (Camb). 2011 Feb 7;47(5):1422-4. doi: 10.1039/c0cc04677a. Epub 2010 Dec 20.

Abstract

Transfer of fatty acyl groups from membrane phospholipids to melittin, a commonly studied membrane-active peptide, has been observed to occur over extended time periods. Transfer can be detected after 1-2 days and selectively targets amino groups at the N-terminal end of the peptide.

MeSH terms

  • Acylation
  • Chromatography, Thin Layer
  • Lipid Bilayers / chemistry*
  • Lipid Bilayers / metabolism
  • Melitten / chemistry*
  • Melitten / metabolism
  • Membrane Lipids / chemistry*
  • Membrane Lipids / metabolism
  • Peptide Fragments / chemistry*
  • Peptide Fragments / metabolism
  • Phosphorylcholine / chemistry*
  • Phosphorylcholine / metabolism
  • Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Substances

  • Lipid Bilayers
  • Membrane Lipids
  • Peptide Fragments
  • Phosphorylcholine
  • Melitten