Comparison between C-reactive protein and adipocyte fatty acid-binding protein as a component of metabolic syndrome in middle-aged women

Clin Biochem. 2011 Mar;44(4):304-6. doi: 10.1016/j.clinbiochem.2010.12.002. Epub 2010 Dec 13.

Abstract

Objectives: We compared the diagnostic accuracy of CRP and adipocyte fatty acid-binding protein (A-FABP) for the metabolic syndrome (MS).

Design and methods: We examined 310 middle-aged Caucasian women.

Results: CRP and AFABP values were significantly associated with the MS probability in the logistic regression model. Operating characteristic curves comparison showed similar areas under the curve.

Conclusions: Measurement of A-FABP is equivalent to CRP in the diagnostic utility of the MS.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adipocytes / metabolism
  • Adult
  • Area Under Curve
  • Biomarkers
  • Blood Glucose / analysis
  • Body Mass Index
  • C-Reactive Protein / metabolism*
  • Case-Control Studies
  • Fatty Acid-Binding Proteins / blood*
  • Female
  • Humans
  • Insulin Resistance
  • Logistic Models
  • Metabolic Syndrome / blood*
  • Metabolic Syndrome / diagnosis*
  • Metabolic Syndrome / physiopathology
  • Middle Aged
  • Obesity / blood
  • Poland
  • White People

Substances

  • Biomarkers
  • Blood Glucose
  • Fatty Acid-Binding Proteins
  • C-Reactive Protein