Disulfide bond as a cleavable linker for molecular self-assembly and hydrogelation

Chem Commun (Camb). 2011 Feb 7;47(5):1619-21. doi: 10.1039/c0cc04135a. Epub 2010 Nov 26.

Abstract

Here we reported on the first example of using the disulfide bond as a cleavable linker to control molecular self-assembly and the formation of small molecular (SM) hydrogels.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Disulfides / chemistry*
  • Hydrogel, Polyethylene Glycol Dimethacrylate / chemistry*
  • Hydrogel, Polyethylene Glycol Dimethacrylate / metabolism*
  • Microscopy, Electron, Transmission
  • Molecular Structure
  • Peptide Fragments / chemistry*
  • Reducing Agents / pharmacology
  • Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Substances

  • Disulfides
  • Peptide Fragments
  • Reducing Agents
  • Hydrogel, Polyethylene Glycol Dimethacrylate