A stabilizing influence: CAL PDZ inhibition extends the half-life of ΔF508-CFTR

Angew Chem Int Ed Engl. 2010 Dec 17;49(51):9907-11. doi: 10.1002/anie.201005585.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adaptor Proteins, Signal Transducing
  • Carrier Proteins / antagonists & inhibitors*
  • Cells, Cultured
  • Cystic Fibrosis Transmembrane Conductance Regulator / chemistry*
  • Enzyme Inhibitors / pharmacology
  • Epithelial Cells
  • Golgi Matrix Proteins
  • Half-Life
  • Humans
  • Membrane Proteins / antagonists & inhibitors*
  • Membrane Transport Proteins
  • Protein Stability
  • Respiratory System / cytology

Substances

  • Adaptor Proteins, Signal Transducing
  • Carrier Proteins
  • Enzyme Inhibitors
  • GOPC protein, human
  • Golgi Matrix Proteins
  • Membrane Proteins
  • Membrane Transport Proteins
  • cystic fibrosis transmembrane conductance regulator delta F508
  • Cystic Fibrosis Transmembrane Conductance Regulator