Destructive weighted Poisson cure rate models

Lifetime Data Anal. 2011 Jul;17(3):333-46. doi: 10.1007/s10985-010-9189-2. Epub 2010 Nov 13.

Abstract

In this paper, we develop a flexible cure rate survival model by assuming the number of competing causes of the event of interest to follow a compound weighted Poisson distribution. This model is more flexible in terms of dispersion than the promotion time cure model. Moreover, it gives an interesting and realistic interpretation of the biological mechanism of the occurrence of event of interest as it includes a destructive process of the initial risk factors in a competitive scenario. In other words, what is recorded is only from the undamaged portion of the original number of risk factors.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Humans
  • Melanoma / surgery
  • Models, Biological*
  • Models, Statistical*
  • Poisson Distribution*
  • Survival Analysis*