A straightjacket for pain?

Simon Beggs; Michael W Salter

doi:10.1016/j.cell.2010.10.038

A straightjacket for pain?

Cell. 2010 Nov 12;143(4):505-7. doi: 10.1016/j.cell.2010.10.038.

Authors

Simon Beggs¹, Michael W Salter

Affiliation

¹ Program in Neurosciences and Mental Health, Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8, Canada.

PMID: 21074043
DOI: 10.1016/j.cell.2010.10.038

Abstract

Perception of pain involves both the peripheral and central nervous systems. Starting with a whole-genome RNA interference screen in Drosophila, Neely et al. (2010) identify a mammalian gene that is required not only for efficient transfer of pain signals between brain centers, but also for the suppression of inappropriate signaling between other sensory systems.

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