Severe affective and behavioural dysregulation is associated with significant psychosocial adversity and impairment

J Child Psychol Psychiatry. 2011 Jun;52(6):686-95. doi: 10.1111/j.1469-7610.2010.02322.x. Epub 2010 Oct 11.

Abstract

Background: Recently, a highly heritable behavioral phenotype of simultaneous deviance on the Anxious/Depressed, Attention Problems, and Aggressive Behavior syndrome scales has been identified on the Child Behavior Checklist (CBCL-Dysregulation Profile, CBCL-DP). This study aims to investigate psychosocial adversity and impairment of the CBCL-DP.

Methods: A total of 9024 patients aged 4-18 years were assessed using the CBCL, and the axes V and VI of ICD-10.

Results: ANOVA revealed significant differences regarding psychosocial adversity and impairment between patients with CBCL-DP phenotype and the clinical control group, patients with attention problems, and patients with attention problems and additional anxious/depressed symptoms as assessed by the CBCL. Patients with CBCL-DP showed significant psychosocial adversity and impairment. However, in most cases patients with aggressive behavior showed equal psychosocial adversity as patients with CBCL-DP.

Conclusions: Findings suggest the CBCL-DP phenotype to be associated with significant psychosocial adversity and impairment either as a cause or an effect of the syndrome. Clinicians should carefully address psychosocial adversity and impairment with particular attention to the adversity and impairment of adolescents with CBCL-DP.

MeSH terms

  • Adolescent
  • Aggression / psychology
  • Anxiety Disorders / diagnosis
  • Anxiety Disorders / epidemiology
  • Anxiety Disorders / genetics
  • Anxiety Disorders / psychology
  • Attention Deficit Disorder with Hyperactivity / diagnosis
  • Attention Deficit Disorder with Hyperactivity / epidemiology
  • Attention Deficit Disorder with Hyperactivity / genetics
  • Attention Deficit Disorder with Hyperactivity / psychology
  • Checklist
  • Child
  • Child Behavior Disorders / diagnosis*
  • Child Behavior Disorders / epidemiology
  • Child Behavior Disorders / genetics
  • Child Behavior Disorders / psychology*
  • Child, Preschool
  • Cross-Sectional Studies
  • Depressive Disorder / diagnosis
  • Depressive Disorder / epidemiology
  • Depressive Disorder / genetics
  • Depressive Disorder / psychology
  • Female
  • Humans
  • Life Change Events*
  • Male
  • Mood Disorders / diagnosis*
  • Mood Disorders / epidemiology
  • Mood Disorders / genetics
  • Mood Disorders / psychology*
  • Parenting / psychology
  • Personality Assessment / statistics & numerical data
  • Psychometrics
  • Risk Factors
  • Social Environment
  • Socioeconomic Factors