Gold nanorods for platinum based prodrug delivery

Chem Commun (Camb). 2010 Nov 28;46(44):8424-6. doi: 10.1039/c0cc03108a. Epub 2010 Oct 11.

Abstract

PEGylated gold nanorods (PEG-GNRs) conjugate with Pt(iv) prodrug as a drug delivery system, showing superior cytotoxicity compared to cisplatin against different types of cancer cells.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cell Line, Tumor
  • Cisplatin / toxicity
  • Drug Carriers / chemistry*
  • Gold / chemistry*
  • Humans
  • Nanotubes / chemistry*
  • Nanotubes / toxicity
  • Platinum / chemistry*
  • Polyethylene Glycols / chemistry
  • Prodrugs / administration & dosage*
  • Prodrugs / toxicity

Substances

  • Drug Carriers
  • Prodrugs
  • Polyethylene Glycols
  • Platinum
  • Gold
  • Cisplatin