Bismuth- and lead-texaphyrin complexes: towards potential α-core emitters for radiotherapy

Chem Commun (Camb). 2010 Nov 14;46(42):7900-2. doi: 10.1039/c0cc03528a. Epub 2010 Oct 4.

Abstract

Lead(II)-texaphyrins and the first discrete binuclear μ-oxo bismuth(III)-texaphyrin are reported. The latter was characterized via single crystal X-ray diffraction analysis. Cell proliferation assays using the A2780 ovarian cancer cell line were used to determine the cytotoxicity of the complexes.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Bismuth / chemistry*
  • Cell Line, Tumor
  • Cell Proliferation
  • Crystallography, X-Ray
  • Female
  • Humans
  • Lead / chemistry*
  • Ovarian Neoplasms / pathology
  • Radiotherapy*

Substances

  • Lead
  • Bismuth