A simple cladding process to apply monolithic silica rods in high performance liquid chromatography

J Chromatogr A. 2010 Nov 5;1217(45):7172-6. doi: 10.1016/j.chroma.2010.09.018. Epub 2010 Sep 16.

Abstract

A simple cladding procedure was developed to apply monolithic silica rods in chromatography. This was used to evaluate the performances of new monolithic silica phases synthesised using a triblock copolymer as a phase separation inducer. The cladding procedure is found efficient after several tests, including scanning electron microscopy and mercury porosimetry, and the obtained columns present a relatively good efficiency in adsorption chromatography (H min is about 50 μm) as compared to other lab-scale developed columns.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adsorption
  • Chromatography, Affinity / methods*
  • Chromatography, High Pressure Liquid / methods*
  • Least-Squares Analysis
  • Mercury
  • Microscopy, Electron, Scanning
  • Permeability
  • Porosity
  • Silicon Dioxide / chemistry*
  • Temperature

Substances

  • Silicon Dioxide
  • Mercury