Cellular automata segmentation of brain tumors on post contrast MR images

Med Image Comput Comput Assist Interv. 2010;13(Pt 3):137-46. doi: 10.1007/978-3-642-15711-0_18.

Abstract

In this paper, we re-examine the cellular automata (CA) algorithm to show that the result of its state evolution converges to that of the shortest path algorithm. We proposed a complete tumor segmentation method on post contrast T1 MR images, which standardizes the VOI and seed selection, uses CA transition rules adapted to the problem and evolves a level set surface on CA states to impose spatial smoothness. Validation studies on 13 clinical and 5 synthetic brain tumors demonstrated the proposed algorithm outperforms graph cut and grow cut algorithms in all cases with a lower sensitivity to initialization and tumor type.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Brain Neoplasms / pathology*
  • Contrast Media*
  • Humans
  • Image Enhancement / methods*
  • Image Interpretation, Computer-Assisted / methods*
  • Magnetic Resonance Imaging / methods*
  • Pattern Recognition, Automated / methods*
  • Reproducibility of Results
  • Sensitivity and Specificity

Substances

  • Contrast Media