First bodipy-DOTA derivatives as probes for bimodal imaging

Chem Commun (Camb). 2010 Nov 21;46(43):8267-9. doi: 10.1039/c0cc02749a. Epub 2010 Sep 29.

Abstract

The synthesis and the photophysical studies of the first bodipy-DOTA and its In(III), Ga(III) and Cu(II) complexes are reported. The introduction of an isothiocyanate handle generates a new bimodal imaging agent capable of both optical and nuclear imaging.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Boron Compounds / chemistry*
  • Coordination Complexes / chemistry*
  • Copper / chemistry
  • Fluorescent Dyes / chemistry*
  • Gallium / chemistry
  • Heterocyclic Compounds, 1-Ring / chemistry*
  • Indium / chemistry
  • Molecular Conformation
  • Positron-Emission Tomography
  • Tomography, Emission-Computed, Single-Photon

Substances

  • 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene
  • Boron Compounds
  • Coordination Complexes
  • Fluorescent Dyes
  • Heterocyclic Compounds, 1-Ring
  • Indium
  • 1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acid
  • Copper
  • Gallium