Genetic analysis of the SNPforID 34-plex ancestry informative SNP panel in Tunisian and Libyan populations

H Khodjet-el-Khil; K Fadhlaoui-Zid; L Cherni; C Phillips; M Fondevila; A Carracedo; A Ben Ammar-Elgaaied

doi:10.1016/j.fsigen.2010.07.007

Genetic analysis of the SNPforID 34-plex ancestry informative SNP panel in Tunisian and Libyan populations

Forensic Sci Int Genet. 2011 Jun;5(3):e45-7. doi: 10.1016/j.fsigen.2010.07.007. Epub 2010 Sep 17.

Authors

H Khodjet-el-Khil¹, K Fadhlaoui-Zid, L Cherni, C Phillips, M Fondevila, A Carracedo, A Ben Ammar-Elgaaied

Affiliation

¹ Laboratory of Genetics, Immunology and Human Pathology, Faculty of Sciences of Tunis, El Manar University, Manar I, 1060 Tunis, Tunisia. housseinkek@yahoo.fr

PMID: 20850402
DOI: 10.1016/j.fsigen.2010.07.007

Abstract

A total of 149 unrelated and healthy individuals comprising: Tunisian Berbers, Tunisians with Andalusian origin and Libyans were typed with the SNPforID 34-plex ancestry informative marker (AIM) SNP panel. Results of 31 of the 34 SNPs are presented and no deviations from Hardy-Weinberg equilibrium were observed after Bonferroni correction (p=0.00161) except rs722098 (p=0.0000). Comparisons of allele frequencies showed high divergence values between North Africans and Europeans (δ>30%) in markers: rs4540055 (allele A) and rs16891982. Our study adds data that can be used as training set genotypes for future ancestry investigations in forensic cases and suggests these AIM-SNPs can successfully differentiate North Africans and Mediterranean Europeans.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Gene Frequency
Genetics, Population*
Humans
Libya
Polymorphism, Single Nucleotide*
Tunisia