[Effect of early local post-irradiation reaction on total and protein-bound hydroxyproline levels in the blood and urine of patients with laryngeal cancer]

Abstract

In 52 laryngeal cancer patients treated by radiotherapy the serum and urine level of hydroxyproline was tested in connection with the intensity of local postirradiation reactions. The serum and urine level were tested by colorimetric method of Proctor and Udenfriend in Tomaszewski modification. In patients with second and third steps of local reaction intensity there was an elevated level of hydroxyproline only in urine. No correlation was observed between the serum level and local reaction.