Long-acting local anesthetics and perioperative pain management

Sharon M Gordon; Anastasia V Mischenko; Raymond A Dionne

doi:10.1016/j.cden.2010.06.002

Long-acting local anesthetics and perioperative pain management

Dent Clin North Am. 2010 Oct;54(4):611-20. doi: 10.1016/j.cden.2010.06.002.

Authors

Sharon M Gordon¹, Anastasia V Mischenko, Raymond A Dionne

Affiliation

¹ Department of Oral-Maxillofacial Surgery, Baltimore College of Dental Surgery, Dental School, University of Maryland, Baltimore, MD 21231, USA. sgordon@umaryland.edu

PMID: 20831925
DOI: 10.1016/j.cden.2010.06.002

Abstract

Although the use of long-acting local anesthetics has become a useful therapeutic approach for managing peri- and postoperative pain, recent evidence reveals unexpected outcomes. This article reviews the clinical use of long-acting local anesthetics, presents current clinical research findings, and makes recommendations for their use.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Anesthesia, Dental / methods*
Anesthetics, Local / adverse effects
Anesthetics, Local / pharmacology*
Anesthetics, Local / therapeutic use
Bupivacaine / adverse effects
Bupivacaine / pharmacology*
Bupivacaine / therapeutic use
Humans
Inflammation / chemically induced
Nociceptors / drug effects
Pain Perception / drug effects
Pain, Postoperative / prevention & control*
Perioperative Care / methods
Time Factors

Substances

Anesthetics, Local
Bupivacaine