[Digital ulcers in systemic sclerosis--an interdisciplinary challenge]

Med Klin (Munich). 2010 Aug;105(8):578-81. doi: 10.1007/s00063-010-1096-5. Epub 2010 Sep 8.
[Article in German]

Abstract

Digital ulcers in systemic sclerosis are painful ischemic necrotic lesions of the acra. Optimal treatment consists of conventional wound management and medication: iloprost infusions promote primary healing of the ulcers, while the dual endothelin receptor antagonist bosentan is used for secondary prophylaxis of new ulcers. The described case illustrates the essential interdisciplinary collaboration for optimal management of these patients.

Publication types

  • Case Reports

MeSH terms

  • Angiography
  • Antihypertensive Agents / therapeutic use
  • Arm / blood supply
  • Bosentan
  • CREST Syndrome / diagnosis*
  • CREST Syndrome / drug therapy
  • Cooperative Behavior*
  • Endothelin Receptor Antagonists
  • Fatal Outcome
  • Fingers*
  • Follow-Up Studies
  • Hand Dermatoses / diagnosis*
  • Hand Dermatoses / drug therapy
  • Humans
  • Iloprost / therapeutic use
  • Interdisciplinary Communication*
  • Leg / blood supply
  • Male
  • Middle Aged
  • Scleroderma, Limited / diagnosis*
  • Scleroderma, Limited / drug therapy
  • Skin Ulcer / diagnosis*
  • Skin Ulcer / drug therapy
  • Sulfonamides / therapeutic use
  • Vasodilator Agents / therapeutic use

Substances

  • Antihypertensive Agents
  • Endothelin Receptor Antagonists
  • Sulfonamides
  • Vasodilator Agents
  • Iloprost
  • Bosentan