Genome gains at chromosome 21q21/22 segment leads to co-amplification of Down Syndrome Critical Regions and known oncogenes in a case of donor cell-derived acute myeloid leukaemia following allogeneic sex mismatched umbilical cord blood transplantation for chronic myeloid leukaemia

Br J Haematol. 2010 Nov;151(3):285-8. doi: 10.1111/j.1365-2141.2010.08350.x. Epub 2010 Aug 25.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Chromosomes, Human, Pair 21 / genetics*
  • Cord Blood Stem Cell Transplantation / adverse effects*
  • Female
  • Gene Amplification
  • Humans
  • Karyotyping
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive / therapy*
  • Leukemia, Myeloid, Acute / etiology*
  • Male
  • Oncogenes
  • Tissue Donors