Posterior revision for failed blebs: long-term outcomes

J Glaucoma. 2011 Aug;20(6):377-82. doi: 10.1097/IJG.0b013e3181eda995.

Abstract

Aim: To report the long-term efficacy and safety of same site revision trabeculectomy with mitomycin application via a posterior approach.

Methods: A noncomparative retrospective case series of consecutive revision trabeculectomies performed for inadequate bleb function between March 2003 and March 2007 by a single surgeon. Surgery involved a posterior/fornix incision with opening of the scleral flap posteriorly at the same site as previous surgery and application of 0.2 to 0.4 mg/mL mitomycin.

Results: Fifty-seven eyes were followed for an average of 33 ± 15 months. Mean baseline intraocular pressure (IOP) reduced from 21.5 ± 6.5 to 11.2 ± 4.4 and 8 ± 3.6 mm Hg at 1 and 5 years, respectively (P<0.001). On Kaplan-Meier survival analysis the probability of maintaining IOP ≤ 15 mm Hg without medication at the end of 1 year was 95% (n=57) and at 3 (n=36) and 5 years (n=7) was 84%. Eighty-five percent of patients were on no antiglaucoma drops at last follow-up. Four cases required a second procedure (7%), transient choroidal effusions occurred in 4 eyes (7%), corneal decompensation in 1 eye (1.7%), and ptosis in 1 (1.7%).

Conclusions: Posterior approach to surgical revision of failed filtration surgery is an effective procedure with good long-term control of IOP.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Alkylating Agents / administration & dosage
  • Combined Modality Therapy
  • Female
  • Follow-Up Studies
  • Glaucoma, Open-Angle / physiopathology
  • Glaucoma, Open-Angle / surgery*
  • Humans
  • Intraocular Pressure / physiology
  • Male
  • Middle Aged
  • Mitomycin / administration & dosage
  • Reoperation
  • Retrospective Studies
  • Sclera / drug effects
  • Surgical Flaps
  • Time Factors
  • Tonometry, Ocular
  • Trabeculectomy*
  • Treatment Failure
  • Treatment Outcome

Substances

  • Alkylating Agents
  • Mitomycin