[Drug therapy for Alzheimer's disease]

Brain Nerve. 2010 Jul;62(7):777-85.
[Article in Japanese]

Abstract

Cholinesterase inhibitors and memantine are widely used for the treatment of Alzheimer disease (AD) and other non-AD dementia worldwide. Since 2000, large scale prospective random control studies using meta-analysis have provided clinical evidence for the use of these drugs in AD and non-AD dementia. Here, we review these reports, including those on other drugs and newly developed drugs, which provide detailed clinical information for the daily management of dementia.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Alzheimer Disease / diagnosis
  • Alzheimer Disease / drug therapy*
  • Alzheimer Disease / etiology
  • Alzheimer Disease / prevention & control
  • Amyloid beta-Peptides
  • Anti-Inflammatory Agents, Non-Steroidal
  • Cholinesterase Inhibitors / therapeutic use*
  • Clioquinol / analogs & derivatives
  • Drug Design*
  • Excitatory Amino Acid Antagonists / therapeutic use
  • Flurbiprofen
  • Indoles
  • Memantine / therapeutic use
  • Meta-Analysis as Topic
  • Randomized Controlled Trials as Topic

Substances

  • AN-1792
  • Amyloid beta-Peptides
  • Anti-Inflammatory Agents, Non-Steroidal
  • Cholinesterase Inhibitors
  • Excitatory Amino Acid Antagonists
  • Indoles
  • PBT2 compound
  • tarenflurbil
  • Flurbiprofen
  • Clioquinol
  • latrepirdine
  • Memantine