[Diagnosis contribution of biomarkers in Alzheimer disease: A case of frontotemporal dementia]

Rev Neurol (Paris). 2011 Feb;167(2):160-3. doi: 10.1016/j.neurol.2010.06.003. Epub 2010 Jul 31.
[Article in French]

Abstract

Introduction: Cerebrospinal fluid biomarkers are a fundamental contribution for the diagnosis of Alzheimer disease, in particular for young people.

Case report: We report a case of Alzheimer disease of a 51-years old man whose clinical presentation corresponded to frontotemporal behavioural criteria. The clinical evaluation noticed some troubles in verbal memory. Only the CSF biomarkers confirmed the diagnosis.

Conclusion: There are different phenotypes of presenile Alzheimer disease and among them we note frontotemporal dementia. It is very important to identify them to introduce a specific treatment.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Alzheimer Disease / cerebrospinal fluid
  • Alzheimer Disease / diagnosis*
  • Alzheimer Disease / physiopathology
  • Biomarkers / cerebrospinal fluid
  • Cerebrovascular Circulation / physiology
  • Electroencephalography
  • Frontotemporal Dementia / cerebrospinal fluid
  • Frontotemporal Dementia / diagnosis*
  • Frontotemporal Dementia / physiopathology
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Neuropsychological Tests
  • Parietal Lobe / blood supply
  • Parietal Lobe / physiopathology

Substances

  • Biomarkers