Do CARs need a driver's license? Adoptive cell therapy with chimeric antigen receptor-redirected T cells has caused serious adverse events

MeSH terms

• Animals
• Clinical Trials as Topic
• Humans
• Immunotherapy, Adoptive / adverse effects*
• Lymphocyte Activation / immunology
• Mice
• Receptors, Antigen / chemistry
• Receptors, Antigen / immunology*
• Recombinant Proteins / chemistry
• Recombinant Proteins / immunology*
• T-Lymphocytes / immunology
• T-Lymphocytes / transplantation*